Google DeepMind Releases Gene Prediction Model AlphaGenome 2

November 11: According to Google DeepMind's official blog, Google DeepMind has released the gene prediction model AlphaGenome 2. Based on a DNA sequence of about 1 million bases and a specified tissue, cell type or state, the model predicts the function of that DNA under those conditions, with readouts covering gene expression, histone modification and chromatin accessibility, plus newly added DNA methylation. Unlike the previous generation, which predicted multiple tissues in parallel, the new model predicts for a single condition at a time, can distinguish between similar cell types, and generalizes to new single-cell data without retraining. DeepMind says it identified nearly twice as many variants affecting cellular gene expression as the previous state-of-the-art model. AlphaGenome 2 is currently open to non-commercial research through the AlphaGenome API, with commercial research in private beta, and the related Skills will launch on Google's agent development platform Antigravity in the near future.